Biology:3-methyleneoxindole reductase
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Short description: Class of enzymes
| 3-methyleneoxindole reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.3.1.17 | ||||||||
| CAS number | 37255-29-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a 3-methyleneoxindole reductase (EC 1.3.1.17) is an enzyme that catalyzes the chemical reaction
- 3-methyl-1,3-dihydroindol-2-one + NADP+ [math]\displaystyle{ \rightleftharpoons }[/math] 3-methylene-1,3-dihydro-2H-indol-2-one + NADPH + H+
Thus, the two substrates of this enzyme are 3-methyl-1,3-dihydroindol-2-one and NADP+, whereas its three products are 3-methylene-1,3-dihydro-2H-indol-2-one, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-methyl-1,3-dihydroindol-2-one:NADP+ oxidoreductase. This enzyme is also termed 3-methyloxindole:NADP+ oxidoreductase.
References
- "Multiple 3-methyleneoxindole reductases of peas, differential inhibition by synthetic auxins". J. Biol. Chem. 242 (5): 1075–7. 1967. PMID 6021071.
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