Biology:4-hydroxyphenylpyruvate decarboxylase

From HandWiki
Short description: Class of enzymes
4-hydroxyphenylpyruvate decarboxylase
Identifiers
EC number4.1.1.80
CAS number109300-96-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The enzyme 4-hydroxyphenylpyruvate decarboxylase (EC 4.1.1.80) catalyzes the chemical reaction

4-hydroxyphenylpyruvate [math]\displaystyle{ \rightleftharpoons }[/math] 4-hydroxyphenylacetaldehyde + CO2

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 4-hydroxyphenylpyruvate carboxy-lyase (4-hydroxyphenylacetaldehyde-forming). This enzyme is also called 4-hydroxyphenylpyruvate carboxy-lyase.

References

  • "Distant precursors of benzylisoquinoline alkaloids and their enzymatic formation". Z. Naturforsch. C: Biosci. 42: 319–332. 1987.