Biology:5-dehydro-2-deoxyphosphogluconate aldolase
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Short description: Class of enzymes
| 5-dehydro-2-deoxyphosphogluconate aldolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.1.2.29 | ||||||||
| CAS number | 62213-25-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme 5-dehydro-2-deoxyphosphogluconate aldolase (EC 4.1.2.29) catalyzes the chemical reaction
- 5-dehydro-2-deoxy-D-gluconate 6-phosphate [math]\displaystyle{ \rightleftharpoons }[/math] glycerone phosphate[1] + malonate semialdehyde
This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase (glycerone-phosphate-forming). Other names in common use include phospho-5-keto-2-deoxygluconate aldolase, 5-dehydro-2-deoxy-D-gluconate-6-phosphate, and malonate-semialdehyde-lyase.
References
- ↑ Glycerone phosphate is often called dihydroxacetone phosphate.
- "The pathway of myo-inositol degradation in Aerobacter aerogenes Conversion of 2-deoxy-5-keto-D-gluconic acid to glycolytic intermediates". J. Biol. Chem. 246 (18): 5662–75. 1971. PMID 4328832.
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