Biology:5-hydroxypentanoate CoA-transferase
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Short description: Class of enzymes
| 5-hydroxypentanoate CoA-transferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.8.3.14 | ||||||||
| CAS number | 111684-68-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a 5-hydroxypentanoate CoA-transferase (EC 2.8.3.14) is an enzyme that catalyzes the chemical reaction
- acetyl-CoA + 5-hydroxypentanoate [math]\displaystyle{ \rightleftharpoons }[/math] acetate + 5-hydroxypentanoyl-CoA
Thus, the two substrates of this enzyme are acetyl-CoA and 5-hydroxypentanoate, whereas its two products are acetate and 5-hydroxypentanoyl-CoA.
This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is acetyl-CoA:5-hydroxypentanoate CoA-transferase. Other names in common use include 5-hydroxyvalerate CoA-transferase, and 5-hydroxyvalerate coenzyme A transferase.
References
- "Properties of 5-hydroxyvalerate CoA-transferase from Clostridium aminovalericum". Biol. Chem. Hoppe-Seyler 371 (11): 1077–82. 1990. doi:10.1515/bchm3.1990.371.2.1077. PMID 2085413.
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