Biology:5alpha-hydroxysteroid dehydratase

From HandWiki
Short description: Class of enzymes
5α-hydroxysteroid dehydratase
Identifiers
EC number4.2.1.62
CAS number9075-27-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The enzyme 5α-hydroxysteroid dehydratase (EC 4.2.1.62) catalyzes the chemical reaction

5α-ergosta-7,22-diene-3β,5-diol [math]\displaystyle{ \rightleftharpoons }[/math] ergosterol + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 5α-ergosta-7,22-diene-3β,5-diol 5,6-hydro-lyase (ergosterol-forming). This enzyme is also called 5α-ergosta-7,22-diene-3β,5-diol 5,6-hydro-lyase.

References

  • "Isolation and purification of a 5 alpha-hydroxysterol dehydrase of yeast". J. Biol. Chem. 245 (9): 2319–27. 1970. PMID 5442273.