Biology:5alpha-hydroxysteroid dehydratase
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Short description: Class of enzymes
5α-hydroxysteroid dehydratase | |||||||||
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Identifiers | |||||||||
EC number | 4.2.1.62 | ||||||||
CAS number | 9075-27-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme 5α-hydroxysteroid dehydratase (EC 4.2.1.62) catalyzes the chemical reaction
- 5α-ergosta-7,22-diene-3β,5-diol [math]\displaystyle{ \rightleftharpoons }[/math] ergosterol + H2O
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 5α-ergosta-7,22-diene-3β,5-diol 5,6-hydro-lyase (ergosterol-forming). This enzyme is also called 5α-ergosta-7,22-diene-3β,5-diol 5,6-hydro-lyase.
References
- "Isolation and purification of a 5 alpha-hydroxysterol dehydrase of yeast". J. Biol. Chem. 245 (9): 2319–27. 1970. PMID 5442273.
Original source: https://en.wikipedia.org/wiki/5alpha-hydroxysteroid dehydratase.
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