Biology:6-phospho-3-hexuloisomerase
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Short description: Class of enzymes
| 6-phospho-3-hexuloisomerase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 5.3.1.27 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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6-phospho-3-hexuloisomerase (EC 5.3.1.27, 3-hexulose-6-phosphate isomerase, phospho-3-hexuloisomerase, PHI, 6-phospho-3-hexulose isomerase, YckF) is an enzyme with systematic name D-arabino-hex-3-ulose-6-phosphate isomerase.[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction
- D-arabino-hex-3-ulose 6-phosphate [math]\displaystyle{ \rightleftharpoons }[/math] D-fructose 6-phosphate
This enzyme plays a key role in the ribulose-monophosphate cycle of formaldehyde fixation.
References
- ↑ "Purification and properties of 3-hexulose phosphate synthase and phospho-3-hexuloisomerase from Methylococcus capsulatus". The Biochemical Journal 144 (3): 477–86. December 1974. doi:10.1042/bj1440477. PMID 4219834.
- ↑ "Assimilation, dissimilation, and detoxification of formaldehyde, a central metabolic intermediate of methylotrophic metabolism". Chemical Record 5 (6): 367–75. 2005. doi:10.1002/tcr.20056. PMID 16278835.
- ↑ "The physiological role of the ribulose monophosphate pathway in bacteria and archaea". Bioscience, Biotechnology, and Biochemistry 70 (1): 10–21. January 2006. doi:10.1271/bbb.70.10. PMID 16428816.
- ↑ "The archaeon Pyrococcus horikoshii possesses a bifunctional enzyme for formaldehyde fixation via the ribulose monophosphate pathway". Journal of Bacteriology 187 (11): 3636–42. June 2005. doi:10.1128/jb.187.11.3636-3642.2005. PMID 15901685.
- ↑ "Crystal structure of MJ1247 protein from M. jannaschii at 2.0 A resolution infers a molecular function of 3-hexulose-6-phosphate isomerase". Structure 10 (2): 195–204. February 2002. doi:10.1016/s0969-2126(02)00701-3. PMID 11839305.
- ↑ "Cloning, purification and characterization of the 6-phospho-3-hexulose isomerase YckF from Bacillus subtilis". Acta Crystallographica Section D 57 (Pt 8): 1138–40. August 2001. doi:10.1107/s090744490100748x. PMID 11468398. http://eprints.lincoln.ac.uk/6181/1/etaylor_1.pdf.
External links
- 6-phospho-3-hexuloisomerase at the US National Library of Medicine Medical Subject Headings (MeSH)
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