Biology:Acetylenecarboxylate hydratase

From HandWiki
Short description: Class of enzymes
acetylenecarboxylate hydratase producing 3-oxopropanoate
Identifiers
EC number4.2.1.27
CAS number9024-26-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The enzyme acetylenecarboxylate hydratase (EC 4.2.1.27) catalyzes the chemical reaction

3-oxopropanoate [math]\displaystyle{ \rightleftharpoons }[/math] propynoate + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 3-oxopropanoate hydro-lyase (propynoate-forming). Other names in common use include acetylenemonocarboxylate hydratase, alkynoate hydratase, acetylenemonocarboxylate hydrase, acetylenemonocarboxylic acid hydrase, malonate-semialdehyde dehydratase, and 3-oxopropanoate hydro-lyase. This enzyme participates in 3 metabolic pathways: beta-alanine metabolism, propanoate metabolism, and butanoate metabolism.

References

  • "Impact of hypothermia on the immunologic response after trauma and elective surgery". Surg. Technol. Int. 14: 41–50. 2005. PMID 16525953. 
  • "Enzymatic utilization of acetylenic compounds. II Acetylenemonocarboxylic acid hydrase". J. Biol. Chem. 234 (4): 941–5. 1959. PMID 13654296.