Biology:Acetylenecarboxylate hydratase
From HandWiki
Short description: Class of enzymes
| acetylenecarboxylate hydratase producing 3-oxopropanoate | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.2.1.27 | ||||||||
| CAS number | 9024-26-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme acetylenecarboxylate hydratase (EC 4.2.1.27) catalyzes the chemical reaction
- 3-oxopropanoate [math]\displaystyle{ \rightleftharpoons }[/math] propynoate + H2O
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 3-oxopropanoate hydro-lyase (propynoate-forming). Other names in common use include acetylenemonocarboxylate hydratase, alkynoate hydratase, acetylenemonocarboxylate hydrase, acetylenemonocarboxylic acid hydrase, malonate-semialdehyde dehydratase, and 3-oxopropanoate hydro-lyase. This enzyme participates in 3 metabolic pathways: beta-alanine metabolism, propanoate metabolism, and butanoate metabolism.
References
- "Impact of hypothermia on the immunologic response after trauma and elective surgery". Surg. Technol. Int. 14: 41–50. 2005. PMID 16525953.
- "Enzymatic utilization of acetylenic compounds. II Acetylenemonocarboxylic acid hydrase". J. Biol. Chem. 234 (4): 941–5. 1959. PMID 13654296.
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