Biology:Acetylenedicarboxylate decarboxylase

From HandWiki
Short description: Class of enzymes
Acetylenedicarboxylate decarboxylase
Identifiers
EC number4.1.1.78
CAS number72561-10-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The enzyme acetylenedicarboxylate decarboxylase (EC 4.1.1.78) catalyzes the chemical reaction

acetylenedicarboxylate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] pyruvate + CO2

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is acetylenedicarboxylate carboxy-lyase (pyruvate-forming). Other names in common use include acetylenedicarboxylate hydratase, acetylenedicarboxylate hydrase, and acetylenedicarboxylate carboxy-lyase. This enzyme participates in pyruvate metabolism.

References

  • "Enzymatic utilization of acetylenic compounds. I. An enzyme converting acetylenedicarboxylic acid to pyruvate". The Journal of Biological Chemistry 233 (3): 706–11. September 1958. PMID 13575441.