Biology:All-trans-octaprenyl-diphosphate synthase
From HandWiki
Short description: Class of enzymes
| All-trans-octaprenyl-diphosphate synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifiers | |||||||||
| EC number | 2.5.1.90 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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All-trans-octaprenyl-diphosphate synthase (EC 2.5.1.90, octaprenyl-diphosphate synthase, octaprenyl pyrophosphate synthetase, polyprenylpyrophosphate synthetase, terpenoidallyltransferase, terpenyl pyrophosphate synthetase, trans-heptaprenyltranstransferase, trans-prenyltransferase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 5 isopentenyl units).[1][2] This enzyme catalyses the following chemical reaction
- (2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate [math]\displaystyle{ \rightleftharpoons }[/math] 5 diphosphate + all-trans-octaprenyl diphosphate
This enzyme catalyses the condensation reactions resulting in the formation of all-trans-octaprenyl diphosphate.
References
- ↑ "Isoprenoid synthesis in Escherichia coli. Separation and partial purification of four enzymes involved in the synthesis". Journal of Biochemistry 99 (5): 1327–37. May 1986. doi:10.1093/oxfordjournals.jbchem.a135600. PMID 3519603.
- ↑ "The identification of Escherichia coli ispB (cel) gene encoding the octaprenyl diphosphate synthase". Biochemical and Biophysical Research Communications 202 (1): 340–5. July 1994. doi:10.1006/bbrc.1994.1933. PMID 8037730.
External links
- All-trans-octaprenyl-diphosphate+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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