Biology:Alpha-gurjunene synthase

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α-gurjunene synthase
Identifiers
EC number4.2.3.72
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

α-Gurjunene synthase (EC 4.2.3.72) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((–)-α-gurjunene-forming).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate [math]\displaystyle{ \rightleftharpoons }[/math] (–)-α-gurjunene + diphosphate

Initial cyclization probably gives bicyclogermacrene in an enzyme-bound form.

References

  1. "Isolation, characterization, and mechanistic studies of (-)-α-gurjunene synthase from Solidago canadensis". Archives of Biochemistry and Biophysics 364 (2): 167–77. April 1999. doi:10.1006/abbi.1999.1122. PMID 10190971. 

External links