Biology:Amine sulfotransferase
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Short description: Class of enzymes
amine sulfotransferase | |||||||||
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Identifiers | |||||||||
EC number | 2.8.2.3 | ||||||||
CAS number | 9026-08-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, an amine sulfotransferase (EC 2.8.2.3) is an enzyme that catalyzes the chemical reaction
- 3'-phosphoadenylyl sulfate + an amine [math]\displaystyle{ \rightleftharpoons }[/math] adenosine 3',5'-bisphosphate + a sulfamate
Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and amine, whereas its two products are adenosine 3',5'-bisphosphate and sulfamate.
This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:amine N-sulfotransferase. Other names in common use include arylamine sulfotransferase, and amine N-sulfotransferase. This enzyme participates in sulfur metabolism.
References
- "Amine N-sulfotransferase". J. Biol. Chem. 262 (21): 10039–43. 1987. PMID 3475273.
- Roy, AB (1960). "The enzymic synthesis of aryl sulphamates". Biochem. J. 74: 49–56.
Original source: https://en.wikipedia.org/wiki/Amine sulfotransferase.
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