Biology:Aminobenzoate decarboxylase

From HandWiki
aminobenzoate decarboxylase
Identifiers
EC number4.1.1.24
CAS number9024-73-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The enzyme aminobenzoate decarboxylase (EC 4.1.1.24) catalyzes the chemical reaction

4(or 2)-aminobenzoate [math]\displaystyle{ \rightleftharpoons }[/math] aniline + CO2

Thus, the two substrates of this enzyme are 4-aminobenzoate and 2-aminobenzoate, whereas its two products are aniline and CO2.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is aminobenzoate carboxy-lyase (aniline-forming). It employs one cofactor, pyridoxal phosphate.

References

  • "Enzymatic decarboxylation of three aminobenzoates". J. Am. Chem. Soc. 79 (3): 628–630. 1957. doi:10.1021/ja01560a032.