Biology:Asparagusate reductase
From HandWiki
| asparagusate reductase | |||||||||
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| Identifiers | |||||||||
| EC number | 1.8.1.11 | ||||||||
| CAS number | 56126-52-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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Asparagusate reductase (EC 1.8.1.11) is an enzyme that catalyzes the chemical reaction
- 3-mercapto-2-mercaptomethylpropanoate + NAD+ [math]\displaystyle{ \rightleftharpoons }[/math] asparagusate + NADH + H+
Thus, the two substrates of this enzyme are 3-mercapto-2-mercaptomethylpropanoate and nicotinamide adenine dinucleotide ion, whereas its 3 products are asparagusate, nicotinamide adenine dinucleotide, and hydrogen ion.
This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-mercapto-2-mercaptomethylpropanoate:NAD+ oxidoreductase. Other names in common use include asparagusate dehydrogenase, asparagusic dehydrogenase, asparagusate reductase (NADH2), and NADH2:asparagusate oxidoreductase.
References
- "Asparagusate dehydrogenases and lipoyl dehydrogenase from asparagus mitochondria". Biochim. Biophys. Acta 384 (2): 342–52. 1975. doi:10.1016/0005-2744(75)90035-2. PMID 1125255.
- "Asparagusate dehydrogenases and lipoyl dehydrogenase from asparagus mitochondria. Physical, chemical, and enzymatic properties". J. Biol. Chem. 251 (12): 3637–44. 1976. PMID 180003.
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