Biology:Benzoin aldolase

From HandWiki
Short description: Enzyme
benzoin aldolase
Identifiers
EC number4.1.2.38
CAS number122097-01-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The enzyme benzoin aldolase (EC 4.1.2.38) catalyzes the chemical reaction

2-hydroxy-1,2-diphenylethanone[1] [math]\displaystyle{ \rightleftharpoons }[/math] 2 benzaldehyde

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase (benzaldehyde-forming)—the systematic name of benzoin is 2-hydroxy-1,2-diphenylethanone. Other names in common use include benzaldehyde lyase, and 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase. It employs one cofactor, thiamin diphosphate.

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 2AG0, 2AG1, and 2UZ1.

References

  1. Also known as benzoin.