Biology:Bile-acid 7alpha-dehydratase
From HandWiki
| Bile-acid 7α-dehydratase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.2.1.106 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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The enzyme bile-acid 7α-dehydratase (EC 4.2.1.106) catalyzes the chemical reaction
- 7α,12α-dihydroxy-3-oxochol-4-enoate [math]\displaystyle{ \rightleftharpoons }[/math] 12α-hydroxy-3-oxochola-4,6-dienoate + H2O
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 7α,12α-dihydroxy-3-oxochol-4-enoate hydro-lyase (12α-hydroxy-3-oxochola-4,6-dienoate-forming). This enzyme is also called 7α,12α-dihydroxy-3-oxochol-4-enoate hydro-lyase.
References
- "Expression and characterization of a C24 bile acid 7 alpha-dehydratase from Eubacterium sp. strain VPI 12708 in Escherichia coli". J. Lipid Res. 37 (6): 1258–67. 1996. PMID 8808760.
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