Biology:Carotenoid 1,2-hydratase

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Carotenoid 1,2-hydratase
Identifiers
EC number4.2.1.131
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Carotenoid 1,2-hydratase (EC 4.2.1.131, CrtC) is an enzyme with systematic name lycopene hydro-lyase (1-hydroxy-1,2-dihydrolycopene-forming).[1][2] This enzyme catalyses the following chemical reaction

(1) 1-hydroxy-1,2-dihydrolycopene [math]\displaystyle{ \rightleftharpoons }[/math] lycopene + H2O
(2) 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene [math]\displaystyle{ \rightleftharpoons }[/math] 1-hydroxy-1,2-dihydrolycopene + H2O

In Rubrivivax gelatinosus and Thiocapsa roseopersicina both products are formed.

References

  1. "Heterologous expression, purification, and enzymatic characterization of the acyclic carotenoid 1,2-hydratase from Rubrivivax gelatinosus". Archives of Biochemistry and Biophysics 414 (1): 51–8. June 2003. doi:10.1016/s0003-9861(03)00099-7. PMID 12745254. 
  2. "Biochemical characterization of the carotenoid 1,2-hydratases (CrtC) from Rubrivivax gelatinosus and Thiocapsa roseopersicina". Applied Microbiology and Biotechnology 91 (4): 1029–36. August 2011. doi:10.1007/s00253-011-3324-1. PMID 21590288. 

External links