Biology:Cerato-platanin
| Cerato-platanin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Cerato-platanin | ||||||||
| Pfam | PF07249 | ||||||||
| Pfam clan | CL0199 | ||||||||
| InterPro | IPR010829 | ||||||||
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In molecular biology, the cerato-platanin family of proteins includes the phytotoxin cerato-platanin (CP) produced by the Ascomycete Ceratocystis platani. CP homologs are also found in both the Ascomycota and the Basidiomycota branches of Dikarya.[1] This toxin causes the severe plant disease: canker stain. This protein occurs in the cell wall of the fungus and is involved in the host-pathogen interaction and induces both cell necrosis and phytoalexin synthesis which is one of the first plant defense-related events. CP, like other fungal surface proteins, is able to self-assemble in vitro.[2] CP is a 120 amino acid protein, containing 40% hydrophobic residues. It is one of the rare examples of protein in which contains a Hopf link.[3] The link is formed by covalent loops - the pieces of protein backbone closed by two disulphide bonds[4] (formed out of four cysteine residues). The N-terminal region of CP is very similar to cerato-ulmin, a phytotoxic protein produced by the Ophiostoma species belonging to the hydrophobin family, which also self-assembles.[5]
References
- ↑ Chen, Hongxin; Kovalchuk, Andriy; Keriö, Susanna; Asiegbu, Fred O. (20 January 2017). "Distribution and bioinformatic analysis of the cerato-platanin protein family in Dikarya". Mycologia 105 (2013): 1479–1488. doi:10.3852/13-115. PMID 23928425.
- ↑ "Atomic force microscopy images suggest aggregation mechanism in cerato-platanin". Eur. Biophys. J. 36 (7): 727–32. September 2007. doi:10.1007/s00249-007-0159-x. PMID 17431609. https://hal.archives-ouvertes.fr/hal-02059668/file/sbcfgpsvzt07.pdf.
- ↑ Dabrowski-Tumanski, Pawel; Sulkowska, Joanna I. (2017-03-28). "Topological knots and links in proteins" (in en). Proceedings of the National Academy of Sciences 114 (13): 3415–3420. doi:10.1073/pnas.1615862114. ISSN 0027-8424. PMID 28280100. Bibcode: 2017PNAS..114.3415D.
- ↑ "Purification, characterization, and amino acid sequence of cerato-platanin, a new phytotoxic protein from Ceratocystis fimbriata f. sp. platani". J. Biol. Chem. 274 (35): 24959–64. August 1999. doi:10.1074/jbc.274.35.24959. PMID 10455173.
- ↑ "Cerato-platanin, a phytotoxic protein from Ceratocystis fimbriata: expression in Pichia pastoris, purification and characterization". Protein Expr. Purif. 49 (2): 159–67. October 2006. doi:10.1016/j.pep.2006.07.006. PMID 16931046.
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