Biology:Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase

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Short description: Class of enzymes
cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
Identifiers
EC number1.3.1.56
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (EC 1.3.1.56) is an enzyme that catalyzes the chemical reaction

  1. REDIRECT Template:Chemical reaction

The two substrates of this enzyme are (1S,2R)-3-phenylcyclohexa-3,5-diene-1,2-diol and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are biphenyl-2,3-diol, reduced NADH, and a proton.[1][2][3]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cis-3-phenylcyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase. This enzyme is also called 2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase. This enzyme participates in biphenyl degradation.[4]

References

  1. ↑ Enzyme 1.3.1.56 at KEGG Pathway Database.
  2. ↑ "Characterization of active recombinant 2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase from Comamonas testosteroni B-356 and sequence of the encoding gene (bphB)". Appl. Environ. Microbiol. 62 (8): 2710–5. 1996. doi:10.1128/aem.62.8.2710-2715.1996. PMID 8702262. Bibcode: 1996ApEnM..62.2710S. 
  3. ↑ "Genetic analysis of a Pseudomonas locus encoding a pathway for biphenyl/polychlorinated biphenyl degradation". Gene 130 (1): 47–55. 1993. doi:10.1016/0378-1119(93)90345-4. PMID 8344527. 
  4. ↑ "Identification of the bphA and bphB genes of Pseudomonas sp. strains KKS102 involved in degradation of biphenyl and polychlorinated biphenyls". Biochem. Biophys. Res. Commun. 202 (2): 850–6. 1994. doi:10.1006/bbrc.1994.2008. PMID 8048958. Bibcode: 1994BBRC..202..850F.