Biology:Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
| cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.3.1.56 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (EC 1.3.1.56) is an enzyme that catalyzes the chemical reaction
- REDIRECT Template:Chemical reaction
The two substrates of this enzyme are (1S,2R)-3-phenylcyclohexa-3,5-diene-1,2-diol and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are biphenyl-2,3-diol, reduced NADH, and a proton.[1][2][3]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cis-3-phenylcyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase. This enzyme is also called 2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase. This enzyme participates in biphenyl degradation.[4]
References
- ↑ Enzyme 1.3.1.56 at KEGG Pathway Database.
- ↑ "Characterization of active recombinant 2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase from Comamonas testosteroni B-356 and sequence of the encoding gene (bphB)". Appl. Environ. Microbiol. 62 (8): 2710–5. 1996. doi:10.1128/aem.62.8.2710-2715.1996. PMID 8702262. Bibcode: 1996ApEnM..62.2710S.
- ↑ "Genetic analysis of a Pseudomonas locus encoding a pathway for biphenyl/polychlorinated biphenyl degradation". Gene 130 (1): 47–55. 1993. doi:10.1016/0378-1119(93)90345-4. PMID 8344527.
- ↑ "Identification of the bphA and bphB genes of Pseudomonas sp. strains KKS102 involved in degradation of biphenyl and polychlorinated biphenyls". Biochem. Biophys. Res. Commun. 202 (2): 850–6. 1994. doi:10.1006/bbrc.1994.2008. PMID 8048958. Bibcode: 1994BBRC..202..850F.
