Biology:Cis-muuroladiene synthase

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cis-Muuroladiene synthase
Identifiers
EC number4.2.3.67
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

cis-Muuroladiene synthase (EC 4.2.3.67, MxpSS1) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cis-muuroladiene-forming).[1] This enzyme catalyses the following chemical reactions

(1) (2E,6E)-farnesyl diphosphate [math]\displaystyle{ \rightleftharpoons }[/math] cis-muurola-3,5-diene + diphosphate
(2) (2E,6E)-farnesyl diphosphate [math]\displaystyle{ \rightleftharpoons }[/math] cis-muurola-4(14),5-diene + diphosphate

The recombinant enzyme from black peppermint produces a mixture of cis-muurola-3,5-diene and cis-muurola-4(14),5-diene.

References

  1. "Cloning and functional characterisation of a cis-muuroladiene synthase from black peppermint (Mentha x piperita) and direct evidence for a chemotype unable to synthesise farnesene". Phytochemistry 67 (15): 1564–71. August 2006. doi:10.1016/j.phytochem.2005.06.012. PMID 16083926. 

External links