Biology:Cyclohexa-1,5-dienecarbonyl-CoA hydratase
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cyclohexa-1,5-dienecarbonyl-CoA hydratase | |||||||||
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Identifiers | |||||||||
EC number | 4.2.1.100 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme cyclohexa-1,5-dienecarbonyl-CoA hydratase (EC 4.2.1.100) catalyzes the chemical reaction
- 6-hydroxycyclohex-1-enecarbonyl-CoA [math]\displaystyle{ \rightleftharpoons }[/math] cyclohexa-1,5-dienecarbonyl-CoA + H2O
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 6-hydroxycyclohex-1-enecarbonyl-CoA (cyclohexa-1,5-dienecarbonyl-CoA-forming). Other names in common use include cyclohexa-1,5-diene-1-carbonyl-CoA hydratase, dienoyl-CoA hydratase, and cyclohexa-1,5-dienecarbonyl-CoA hydro-lyase (incorrect). This enzyme participates in benzoate degradation via CoA ligation.
References
- "Cyclohexa-1,5-diene-1-carbonyl-CoA hydratase [corrected], an enzyme involved in anaerobic metabolism of benzoyl-CoA in the denitrifying bacterium Thauera aromatica". Eur. J. Biochem. 255 (3): 618–27. 1998. doi:10.1046/j.1432-1327.1998.2550618.x. PMID 9738901.
- "Shedding light on anaerobic benzene ring degradation: a process unique to prokaryotes?". J. Bacteriol. 179 (2): 301–9. 1997. PMID 8990279.
- "Products of enzymatic reduction of benzoyl-CoA, a key reaction in anaerobic aromatic metabolism". Eur. J. Biochem. 211 (3): 649–61. 1993. doi:10.1111/j.1432-1033.1993.tb17593.x. PMID 8436125.
![]() | Original source: https://en.wikipedia.org/wiki/Cyclohexa-1,5-dienecarbonyl-CoA hydratase.
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