Biology:Cyclohexyl-isocyanide hydratase
From HandWiki
| cyclohexyl-isocyanide hydratase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.2.1.103 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme cyclohexyl-isocyanide hydratase (EC 4.2.1.103) catalyzes the chemical reaction
- N-cyclohexylformamide [math]\displaystyle{ \rightleftharpoons }[/math] cyclohexyl isocyanide + H2O
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is N-cyclohexylformamide hydro-lyase (cyclohexyl-isocyanide-forming). Other names in common use include isonitrile hydratase, and N-cyclohexylformamide hydro-lyase. This enzyme participates in caprolactam degradation.
References
- "Discovery of a novel enzyme, isonitrile hydratase, involved in nitrogen-carbon triple bond cleavage". J. Biol. Chem. 276 (26): 23480–5. 2001. doi:10.1074/jbc.M007856200. PMID 11306561.
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