Biology:D(−)-tartrate dehydratase

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Short description: Enzyme
D(−)-tartrate dehydratase
Identifiers
EC number4.2.1.81
CAS number82532-88-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The enzyme D(−)-tartrate dehydratase (EC 4.2.1.81) catalyzes the chemical reaction

(S,S)-tartrate [math]\displaystyle{ \rightleftharpoons }[/math] oxaloacetate + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (S,S)-tartrate hydro-lyase (oxaloacetate-forming). Other names in common use include D-tartrate dehydratase, and (S,S)-tartrate hydro-lyase. It has 2 cofactors: iron and manganese.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2DW6 and 2DW7.

References