Biology:D-lyxose ketol-isomerase
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Short description: Class of enzymes
| D-lyxose ketol-isomerase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 5.3.1.15 | ||||||||
| CAS number | 37318-42-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a D-lyxose ketol-isomerase (EC 5.3.1.15) is an enzyme that catalyzes the chemical reaction
- D-lyxose [math]\displaystyle{ \rightleftharpoons }[/math] D-xylulose
Hence, this enzyme has one substrate, D-lyxose, and one product, D-xylulose.
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is D-lyxose aldose-ketose-isomerase. Other names in common use include D-lyxose isomerase, and D-lyxose ketol-isomerase. This enzyme participates in pentose and glucuronate interconversions.
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1QO2 and 1VZW.
References
- "Purification and Characterization of D-Lyxose Isomerase". J. Biol. Chem. 240: 2367–72. 1965. PMID 14304839.
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