Biology:D-sedoheptulose 7-phosphate isomerase
From HandWiki
| D-sedoheptulose 7-phosphate isomerase | |||||||||
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| Identifiers | |||||||||
| EC number | 5.3.1.28 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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D-sedoheptulose 7-phosphate isomerase (EC 5.3.1.28, sedoheptulose-7-phosphate isomerase, phosphoheptose isomerase, gmhA (gene), lpcA (gene)) is an enzyme with systematic name D-glycero-D-manno-heptose 7-phosphate aldose-ketose-isomerase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction
- D-sedoheptulose 7-phosphate [math]\displaystyle{ \rightleftharpoons }[/math] D-glycero-D-manno-heptose 7-phosphate
In Gram-negative bacteria the enzyme is involved in biosynthesis of ADP-L-glycero-β-D-manno-heptose.
References
- ↑ "Biosynthesis pathway of ADP-L-glycero-β-D-manno-heptose in Escherichia coli". Journal of Bacteriology 184 (2): 363–9. January 2002. doi:10.1128/jb.184.2.363-369.2002. PMID 11751812.
- ↑ "Biosynthesis of nucleotide-activated D-glycero-D-manno-heptose". The Journal of Biological Chemistry 276 (24): 20935–44. June 2001. doi:10.1074/jbc.m100378200. PMID 11279237.
- ↑ "Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides". Microbiology 148 (Pt 7): 1979–89. July 2002. doi:10.1099/00221287-148-7-1979. PMID 12101286.
- ↑ "A preliminary X-ray study of sedoheptulose-7-phosphate isomerase from Burkholderia pseudomallei". Acta Crystallographica Section F 65 (Pt 11): 1110–2. November 2009. doi:10.1107/s174430910903259x. PMID 19923728.
- ↑ "Structure and function of sedoheptulose-7-phosphate isomerase, a critical enzyme for lipopolysaccharide biosynthesis and a target for antibiotic adjuvants". The Journal of Biological Chemistry 283 (5): 2835–45. February 2008. doi:10.1074/jbc.m706163200. PMID 18056714.
External links
- D-sedoheptulose+7-phosphate+isomerase at the US National Library of Medicine Medical Subject Headings (MeSH)
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