Biology:Dehydro-L-gulonate decarboxylase

From HandWiki
dehydro-L-gulonate decarboxylase
Identifiers
EC number4.1.1.34
CAS number9024-67-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The enzyme dehydro-L-gulonate decarboxylase (EC 4.1.1.34) catalyzes the chemical reaction

3-dehydro-L-gulonate [math]\displaystyle{ \rightleftharpoons }[/math] L-xylulose + CO2

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3-dehydro-L-gulonate carboxy-lyase (L-xylulose-forming). This enzyme participates in pentose and glucuronate interconversions.

References

  • "Purification and properties of beta-L-hydroxy acid dehydrogenase II. Isolation of beta-keto-L-gluconic acid, an intermediate in L-xylulose biosynthesis". J. Biol. Chem. 236: 357–364. 1961.