Biology:Epoetin theta

From HandWiki
Epoetin theta
Clinical data
Trade namesBiopoin, Eporatio
ATC code
  • None
Legal status
Legal status
Identifiers
CAS Number
PubChem SID
DrugBank
UNII
Chemical and physical data
FormulaC815H1317N233O241S5
Molar mass18396.19 g·mol−1

Epoetin theta, sold under the brand name Biopoin among others, is a form of the human hormone erythropoietin produced using recombinant DNA technology.[1][2]

It acts as a short acting erythropoiesis-stimulating agent (ESA) for the treatment of anemia associated with chronic kidney disease and chemotherapy-induced anemia in patients with cancer.[3]

Medical uses

Epoetin theta is indicated for the treatment of symptomatic anemia in adults.[1]

Side effects

The most common side effects include shunt thrombosis (clots that can form in blood vessels of patients on dialysis, a blood clearance technique), headache, hypertension (high blood pressure), hypertensive crisis (sudden, dangerously high blood pressure), skin reactions, arthralgia (joint pain) and influenza (flu)-like illness.[1] Epoetin theta was authorized for medical use in the European Union in October 2009.[1] It is on the World Health Organization's List of Essential Medicines.[4]


References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 "Biopoin EPAR". 16 December 2009. https://www.ema.europa.eu/en/medicines/human/EPAR/biopoin.  Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
  2. ↑ 2.0 2.1 "Eporatio EPAR". 16 December 2009. https://www.ema.europa.eu/en/medicines/human/EPAR/eporatio.  Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
  3. ↑ "Dose efficiency of erythropoiesis-stimulating agents for the treatment of patients with chemotherapy-induced anemia: a systematic review". Clinical Therapeutics 36 (4): 594–610. April 2014. doi:10.1016/j.clinthera.2014.02.007. PMID 24656152. 
  4. ↑ World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. 2021. WHO/MHP/HPS/EML/2021.02. 

attribution contains material copied from Biopoin | European Medicines Agency https://www.ema.europa.eu/en/medicines/human/EPAR/biopoin 2021