Biology:Ethylmalonyl-CoA decarboxylase

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Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example
Ethylmalonyl-CoA decarboxylase
Identifiers
EC number4.1.1.94
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Ethylmalonyl-CoA decarboxylase (EC 4.1.1.94) is an enzyme with systematic name (S)-ethylmalonyl-CoA carboxy-lyase (butanoyl-CoA-forming).[1] This enzyme catalyses the following chemical reaction

(S)-ethylmalonyl-CoA [math]\displaystyle{ \rightleftharpoons }[/math] butanoyl-CoA + CO2

The vertebrate enzyme decarboxylates ethylmalonyl-CoA.

References

  1. "Ethylmalonyl-CoA decarboxylase, a new enzyme involved in metabolite proofreading". The Journal of Biological Chemistry 286 (50): 42992–3003. Dec 2011. doi:10.1074/jbc.m111.281527. PMID 22016388. 

External links