Biology:Flavonol 3-sulfotransferase

From HandWiki
Short description: Class of enzymes
flavonol 3-sulfotransferase
Identifiers
EC number2.8.2.25
CAS number121855-10-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a flavonol 3-sulfotransferase (EC 2.8.2.25) is an enzyme that catalyzes the chemical reaction

3'-phosphoadenylyl sulfate + flavonol[math]\displaystyle{ \rightleftharpoons }[/math] adenosine 3',5'-bisphosphate + flavonol 3-sulfate

Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and a flavonol, whereas its two products are adenosine 3',5'-bisphosphate and flavonol 3-sulfate. A specific examples of a flavonol that can act as a substrate is quercetin.[1]

This enzyme belongs to the family of transferases termed the sulfotransferases, which transfer sulfate groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:flavonol 3-sulfotransferase.

References