Biology:GSK3A
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Glycogen synthase kinase-3 alpha is an enzyme that in humans is encoded by the GSK3A gene.[1]
Glycogen synthase kinase 3-alpha EC 2.7.1.37 is a multifunctional protein serine kinase, homologous to Drosophila 'shaggy' (zeste-white3) and implicated in the control of several regulatory proteins including glycogen synthase and various transcription factors (e.g., JUN). It also plays a role in the WNT and phosphoinositide 3-kinase (especially PIK3CG) signaling pathways.[2][3]
See also
- Glycogen synthase kinase 3
References
- ↑ "Isolation and chromosomal mapping of human glycogen synthase kinase-3 alpha and -3 beta encoding genes". Genome 41 (5): 720–7. Oct 1998. doi:10.1139/gen-41-5-720. PMID 9809441.
- ↑ "Glycogen synthase kinase-3: properties, functions, and regulation". Chemical Reviews 101 (8): 2527–40. Aug 2001. doi:10.1021/cr000110o. PMID 11749387.
- ↑ "Entrez Gene: GSK3A glycogen synthase kinase 3 alpha". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2931.
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