Biology:Gamma-humulene synthase

From HandWiki
γ-humulene synthase
Identifiers
EC number4.2.3.56
CAS number110639-19-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

γ-Humulene synthase (EC 4.2.3.56, humulene cyclase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (γ-humulene-forming).[1][2] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate [math]\displaystyle{ \rightleftharpoons }[/math] γ-humulene + diphosphate

References

  1. "Sesquiterpene synthases from grand fir (Abies grandis). Comparison of constitutive and wound-induced activities, and cDNA isolation, characterization, and bacterial expression of delta-selinene synthase and γ-humulene synthase". The Journal of Biological Chemistry 273 (4): 2078–89. January 1998. doi:10.1074/jbc.273.4.2078. PMID 9442047. 
  2. "Alteration of product formation by directed mutagenesis and truncation of the multiple-product sesquiterpene synthases δ-selinene synthase and γ-humulene synthase". Archives of Biochemistry and Biophysics 402 (1): 120–35. June 2002. doi:10.1016/S0003-9861(02)00068-1. PMID 12051690. 

External links