Biology:Gentisate decarboxylase
From HandWiki
| gentisate decarboxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.1.1.62 | ||||||||
| CAS number | 37290-54-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme gentisate decarboxylase (EC 4.1.1.62) catalyzes the chemical reaction
- 2,5-dihydroxybenzoate [math]\displaystyle{ \rightleftharpoons }[/math] hydroquinone + CO2
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2,5-dihydroxybenzoate carboxy-lyase (hydroquinone-forming). Other names in common use include 2,5-dihydroxybenzoate decarboxylase, and gentisate carboxy-lyase. This enzyme participates in tyrosine metabolism.
References
- "The non-oxidative decarboxylation of p-hydroxybenzoic acid, gentisic acid, protocatechuic acid and gallic acid by Klebsiella aerogenes (Aerobacter aerogenes)". Antonie van Leeuwenhoek 35 (3): 325–43. 1969. doi:10.1007/BF02219153. PMID 5309907.
 |  |
