Biology:Gentisate decarboxylase

From HandWiki
gentisate decarboxylase
Identifiers
EC number4.1.1.62
CAS number37290-54-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The enzyme gentisate decarboxylase (EC 4.1.1.62) catalyzes the chemical reaction

2,5-dihydroxybenzoate [math]\displaystyle{ \rightleftharpoons }[/math] hydroquinone + CO2

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2,5-dihydroxybenzoate carboxy-lyase (hydroquinone-forming). Other names in common use include 2,5-dihydroxybenzoate decarboxylase, and gentisate carboxy-lyase. This enzyme participates in tyrosine metabolism.

References

  • "The non-oxidative decarboxylation of p-hydroxybenzoic acid, gentisic acid, protocatechuic acid and gallic acid by Klebsiella aerogenes (Aerobacter aerogenes)". Antonie van Leeuwenhoek 35 (3): 325–43. 1969. doi:10.1007/BF02219153. PMID 5309907.