Biology:Geranyl-pyrophosphate—olivetolic acid geranyltransferase

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Geranyl-pyrophosphate—olivetolic acid geranyltransferase
Identifiers
EC number2.5.1.102
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Geranyl-pyrophosphate—olivetolic acid geranyltransferase (EC 2.5.1.102, GOT) is an enzyme with systematic name geranyl-diphosphate:olivetolate geranyltransferase.[1] This enzyme catalyses the following chemical reaction

geranyl diphosphate + 2,4-dihydroxy-6-pentylbenzoate [math]\displaystyle{ \rightleftharpoons }[/math] diphosphate + cannabigerolate

Part of the cannabinoids biosynthetic pathway of the plant Cannabis sativa.

References

  1. "Prenylation of olivetolate by a hemp transferase yields cannabigerolic acid, the precursor of tetrahydrocannabinol". FEBS Letters 427 (2): 283–5. May 1998. doi:10.1016/S0014-5793(98)00450-5. PMID 9607329. 

External links