Biology:Geranylgeranyl diphosphate reductase

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Short description: Class of enzymes
Geranylgeranyl diphosphate reductase
Identifiers
EC number1.3.1.83
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Geranylgeranyl diphosphate reductase (EC 1.3.1.83, geranylgeranyl reductase, CHL P) is an enzyme with systematic name geranylgeranyl-diphosphate:NADP+ oxidoreductase.[1][2][3] This enzyme catalises the following chemical reaction

phytyl diphosphate + 3 NADP+ [math]\displaystyle{ \rightleftharpoons }[/math] geranylgeranyl diphosphate + 3 NADPH + 3 H+

This enzyme also acts on geranylgeranyl-chlorophyll a.

References

  1. "Hydrogenation of geranylgeraniol : two pathways exist in spinach chloroplasts". Plant Physiology 71 (4): 849–54. April 1983. doi:10.1104/pp.71.4.849. PMID 16662918. 
  2. "Reduced activity of geranylgeranyl reductase leads to loss of chlorophyll and tocopherol and to partially geranylgeranylated chlorophyll in transgenic tobacco plants expressing antisense RNA for geranylgeranyl reductase". Plant Physiology 120 (3): 695–704. July 1999. doi:10.1104/pp.120.3.695. PMID 10398704. 
  3. "Metabolic compartmentation of plastid prenyllipid biosynthesis--evidence for the involvement of a multifunctional geranylgeranyl reductase". European Journal of Biochemistry 251 (1-2): 413–7. January 1998. doi:10.1046/j.1432-1327.1998.2510413.x. PMID 9492312. 

External links