Biology:HCP5
From HandWiki
The gene known as HCP5 (HLA Complex P5) is a human endogenous retrovirus, meaning that it is a fossil of an ancient virus that at one time infected people, but has now become an integral part of the human genome.[1] One variation of HCP5 appears to provide some delay or resistance to the development of AIDS when a person is infected with HIV. This variation of HCP5 frequently occurs in conjunction with a particular version of an immune system gene called HLA-B.[1]
HCP5 has been reported to become upregulated after human papillomavirus infection and may promote the development of cervical cancer.[2][3]
Notes and references
- ↑ 1.0 1.1 AIDS Abated, B. Vastag, Science News Vol.172 No.3, 21 July 2007
- ↑ "Association of genomic variants at the Human Leukocyte Antigen locus with cervical cancer risk, HPV status, and gene expression levels". Int J Cancer. doi:10.1002/ijc.33171. PMID 32580243.
- ↑ "LncRNA HCP5 promotes the development of cervical cancer by regulating MACC1 via suppression of microRNA-15a". Eur Rev Med Pharmacol Sci. doi:10.26355/eurrev_201808_15616. PMID 30070314.
 |  |
