Biology:Isoliquiritigenin 2'-O-methyltransferase
From HandWiki
| Isoliquiritigenin 2'-O-methyltransferase | |||||||||
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| Identifiers | |||||||||
| EC number | 2.1.1.154 | ||||||||
| CAS number | 139317-14-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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In enzymology, an isoliquiritigenin 2'-O-methyltransferase (EC 2.1.1.154) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + isoliquiritigenin [math]\displaystyle{ \rightleftharpoons }[/math] S-adenosyl-L-homocysteine + 2'-O-methylisoliquiritigenin
Thus, the two substrates of this enzyme are S-adenosyl methionine and isoliquiritigenin, whereas its two products are S-adenosylhomocysteine and 2'-O-methylisoliquiritigenin.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:isoliquiritigenin 2'-O-methyltransferase. Other names in common use include chalcone OMT, and CHMT.
References
- "Identification, purification, and characterization of S-adenosyl-L-methionine: isoliquiritigenin 2'-O-methyltransferase from alfalfa (Medicago sativa L.)". Arch. Biochem. Biophys. 293 (1): 158–66. 1992. doi:10.1016/0003-9861(92)90379-B. PMID 1731632.
- "Enzymic O-methylation of isoliquiritigenin and licodione in alfalfa and licorice cultures". Phytochemistry 44 (6): 991–5. 1997. doi:10.1016/S0031-9422(96)00670-X. PMID 9055445.
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