Biology:Isoprene synthase
From HandWiki
| Isoprene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.2.3.27 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
 | This article includes a list of references, but its sources remain unclear because it has insufficient inline citations. (August 2025) (Learn how and when to remove this template message) |
The enzyme isoprene synthase (EC 4.2.3.27) catalyzes the chemical reaction
- prenyl pyrophosphate isoprene + diphosphate
This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is prenyl-diphosphate diphosphate-lyase (isoprene-forming). Other names in common use include ISPC, and ISPS. The crystal structure of ISPS was the first of a hemiterpene synthase and was reported by the research group of David W. Christianson at the University of Pennsylvania.[1]
References
- ↑ Köksal, Mustafa; Zimmer, Ina; Schnitzler, Jörg-Peter; Christianson, David W. (September 2010). "Structure of Isoprene Synthase Illuminates the Chemical Mechanism of Teragram Atmospheric Carbon Emission". Journal of Molecular Biology 402 (2): 363–373. doi:10.1016/j.jmb.2010.07.009. PMID 20624401.
Further reading
- "Enzymatic Synthesis of Isoprene from Dimethylallyl Diphosphate in Aspen Leaf Extracts". Plant Physiology 97 (4): 1588–1591. 1991. doi:10.1104/pp.97.4.1588. PMID 16668590.
- "Characterization of aspen isoprene synthase, an enzyme responsible for leaf isoprene emission to the atmosphere". Journal of Biological Chemistry 270 (22): 13010–6. 1995. doi:10.1074/jbc.270.22.13010. PMID 7768893.
- "Light-Dependent Isoprene Emission (Characterization of a Thylakoid-Bound Isoprene Synthase in Salix discolor Chloroplasts)". Plant Physiology 112 (1): 171–182. 1996. doi:10.1104/pp.112.1.171. PMID 12226383.
- "Characterization of an Isoprene Synthase from Leaves of Quercus petraea (Mattuschka) Liebl.". Botanica Acta 109 (3): 216–221. 1996. doi:10.1111/j.1438-8677.1996.tb00566.x. Bibcode: 1996BotAc.109..216S.
- "First isolation of an isoprene synthase gene from poplar and successful expression of the gene in Escherichia coli". Planta 213 (3): 483–7. 2001. doi:10.1007/s004250100557. PMID 11506373. Bibcode: 2001Plant.213..483M.
- "Isoprene synthase activity parallels fluctuations of isoprene release during growth of Bacillus subtilis". Biochemical and Biophysical Research Communications 294 (1): 71–5. 2002. doi:10.1016/S0006-291X(02)00435-7. PMID 12054742. Bibcode: 2002BBRC..294...71S.
- "Gene expression and characterization of isoprene synthase from Populus alba". FEBS Letters 579 (11): 2514–8. 2005. doi:10.1016/j.febslet.2005.03.066. PMID 15848197. Bibcode: 2005FEBSL.579.2514S.
- "Biochemical properties of isoprene synthase in poplar (Populus x canescens)". Planta 222 (5): 777–86. 2005. doi:10.1007/s00425-005-0022-1. PMID 16052321.
- "Isoprene synthesis protects transgenic tobacco plants from oxidative stress". Plant, Cell & Environment 32 (5): 520–31. 2009. doi:10.1111/j.1365-3040.2009.01946.x. PMID 19183288. Bibcode: 2009PCEnv..32..520V.
- "Genetic structure and regulation of isoprene synthase in Poplar (Populus spp.)". Plant Molecular Biology 73 (4–5): 547–58. 2010. doi:10.1007/s11103-010-9642-3. PMID 20467886. Bibcode: 2010PMolB..73..547V.
- "Isoprene synthesis in plants – lessons from a transgenic tobacco model". Plant, Cell & Environment 34 (6): 1043–53. 2011. doi:10.1111/j.1365-3040.2011.02303.x. PMID 21388420. Bibcode: 2011PCEnv..34.1043V.
 |  |
