Biology:Lactobacillus jensenii
| Lactobacillus jensenii | |
|---|---|
Scientific classification 
| |
| Domain: | Bacteria |
| Phylum: | Bacillota |
| Class: | Bacilli |
| Order: | Lactobacillales |
| Family: | Lactobacillaceae |
| Genus: | Lactobacillus |
| Species: | L. jensenii
|
| Binomial name | |
| Lactobacillus jensenii Falsen et al. 1999
| |
Lactobacillus jensenii is a normal inhabitant of the lower reproductive tract in healthy women.[1][2][3] L. jensenii makes up 23% of vaginal microflora that is naturally occurring. It is also found on the skins of grapes at the time of their harvest.[4][5][6] L. jensenii is sometimes used in producing fermented foods.[7]
Lactobacillus jensenii produces enzymes that cause hydrolase release from the liver. Hydrolase aids in the digestion of food in the upper gastrointestinal tract.
Lactobacillus jensenii and other Lactobacillus species that produce hydrogen peroxide, (most notably L. crispatus), have been correlated with a decreased rate of bacterial vaginosis, gonorrhea- and HIV-acquisition and pelvic inflammatory disease.[4][8] A stable colonization with these species, as opposed to dominantly L. iners, is associated with better reproductive outcomes, e.g. a decreased rate of preterm birth.[8]
Discovery
Lactobacillus jensenii was discovered by F. Gasser, M. Mandel, and M. Rogosa in 1969. Although sharing many characterization criteria, L. jensenii differed from the similar Lactobacillus leichmannii in a gel electrophoresis analysis of their respective lactic dehydrogenases.[9] The species was named in honour of Sigurd Orla-Jensen, a Danish microbiologist and a pioneer of biotechnology.
Characterization
Lactobacillus jensenii is Gram-positive, rod-shaped, negative for catalase and oxidase, and anaerobic. The organism can grow on blood agar.[6]
Morphology
Colonies of L. jensenii are circular, colorless, small, and translucent.[6]
Infection
Bloodstream infection by Lactobacilli is rare but often fatal, with 30% of endocarditis cases caused by the genus resulting in patient mortality.[7] While L. jensenii takes advantage of nonimmunocompetence in patients, immunocompetent cases have also been observed.[7]
Treatment
In the rare occurrence of infection, L. jensenii can be treated with teicoplanin and meropenem.[7]
References
- ↑ Nardis, C.; Mastromarino, P.; Mosca, L. (September 2013). "Vaginal microbiota and viral sexually transmitted diseases". Annali di Igiene 25 (5): 443–56. doi:10.7416/ai.2013.1946. PMID 24048183.
- ↑ Bennett, John (2015). Mandell, Douglas, and Bennett's principles and practice of infectious diseases. Philadelphia, PA: Elsevier/Saunders. ISBN 9781455748013; Access provided by the University of Pittsburgh
- ↑ Prince, Amanda L.; Antony, Kathleen M.; Chu, Derrick M.; Aagaard, Kjersti M. (2014). "The microbiome, parturition, and timing of birth: more questions than answers". Journal of Reproductive Immunology 104–105: 12–19. doi:10.1016/j.jri.2014.03.006. ISSN 0165-0378. PMID 24793619.
- ↑ 4.0 4.1 May A. D. Antonio; Stephen E. Hawes; Sharon L. Hillier (12 November 1999). "The Identification of Vaginal Lactobacillus species and the Demographic and Microbiologic Characteristics of Women Colonized by These Species". The Journal of Infectious Diseases 180 (6): 1950–1956. doi:10.1086/315109. PMID 10558952.
- ↑ Hidemi S. Yasamoto; Qiang Xu; Raina N. Fichorova (8 January 2013). "Homeostatic properties of Lactobacillus jensenii engineered as a live vaginal anti-HIV microbicide". BMC Microbiology 13 (4): 4. doi:10.1186/1471-2180-13-4. PMID 23298379.
- ↑ 6.0 6.1 6.2 "Lactobacillus jensenii". The Regents of the University of California, Davis campus. 18 August 2014. http://wineserver.ucdavis.edu/industry/enology/winemicro/winebacteria/lactobacillus_jensenii.html.
- ↑ 7.0 7.1 7.2 7.3 Piera Assunta Fradiani; Andrea Petrucca; Fiorentina Ascenzioni; Giandomenico Di Nucci; Antonella Teggi; Silvia Bilancini; Paolo Cipriani (28 January 2010). "Endocarditis caused by Lactobacillus jensenii in an immunocompetent patient". Journal of Medical Microbiology 59 (5): 607–609. doi:10.1099/jmm.0.017764-0. PMID 20133416. http://www.microbiologyresearch.org/docserver/fulltext/jmm/59/5/607.pdf?expires=1480719591&id=id&accname=guest&checksum=FBB03FDD34123BBE1943A859CE4BDDE3.
- ↑ 8.0 8.1 Mitchell, Caroline; Manhart, Lisa E.; Thomas, Kathy; Fiedler, Tina; Fredricks, David N.; Marrazzo, Jeanne (2012). "Behavioral Predictors of Colonization with Lactobacillus crispatus or Lactobacillus jensenii after Treatment for Bacterial Vaginosis: A Cohort Study". Infectious Diseases in Obstetrics and Gynecology 2012 (Special Issue on The Infections of Lower Genital Tract): 1–6. doi:10.1155/2012/706540. ISSN 1064-7449. PMID 22693410.
- ↑ F. Gasser; M. Mandel; M. Rogosa (29 April 1970). "Lactobacillus jensenii sp. nov., a New Representative of the Subgenus Thermobacterium". Journal of General Microbiology 62 (2): 219–222. doi:10.1099/00221287-62-2-219. PMID 5493596. http://www.microbiologyresearch.org/docserver/fulltext/micro/62/2/mic-62-2-219.pdf?expires=1480719063&id=id&accname=guest&checksum=429F20CCBC5627EBA42AE58CBE8973A7.
External links
Wikidata ☰ Q2618197 entry
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