Biology:Molybdenum cofactor sulfurtransferase

From HandWiki
Molybdenum cofactor sulfurtransferase
Identifiers
EC number2.8.1.9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Molybdenum cofactor sulfurtransferase (EC 2.8.1.9, molybdenum cofactor sulfurase, ABA3, MoCo sulfurase, MoCo sulfurtransferase) is an enzyme with systematic name L-cysteine:molybdenum cofactor sulfurtransferase.[1][2][3] This enzyme catalyses the following chemical reaction

molybdenum cofactor + L-cysteine + 2 H+ [math]\displaystyle{ \rightleftharpoons }[/math] thio-molybdenum cofactor + L-alanine + H2O

This enzyme contains pyridoxal phosphate.

References

  1. "ABA3 is a molybdenum cofactor sulfurase required for activation of aldehyde oxidase and xanthine dehydrogenase in Arabidopsis thaliana". The Journal of Biological Chemistry 276 (44): 40381–4. November 2001. doi:10.1074/jbc.c100472200. PMID 11553608. 
  2. "Characterization of the NifS-like domain of ABA3 from Arabidopsis thaliana provides insight into the mechanism of molybdenum cofactor sulfuration". The Journal of Biological Chemistry 280 (6): 4213–8. February 2005. doi:10.1074/jbc.m411195200. PMID 15561708. 
  3. "Binding of sulfurated molybdenum cofactor to the C-terminal domain of ABA3 from Arabidopsis thaliana provides insight into the mechanism of molybdenum cofactor sulfuration". The Journal of Biological Chemistry 283 (15): 9642–50. April 2008. doi:10.1074/jbc.m708549200. PMID 18258600. 

External links