Biology:OR4E2

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

Olfactory receptor 4E2 is a protein that in humans is encoded by the OR4E2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• "The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA.". Genomics 19 (3): 478–93. 1994. doi:10.1006/geno.1994.1097. PMID 8188290. 
• "Analysis of the 1.1-Mb human alpha/delta T-cell receptor locus with bacterial artificial chromosome clones.". Genome Res. 7 (4): 330–8. 1997. doi:10.1101/gr.7.4.330. PMID 9110172. 
• "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295–302. 2003. doi:10.1006/geno.2002.6830. PMID 12213199. 
• "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. 2004. doi:10.1073/pnas.0307882100. PMID 14983052. Bibcode: 2004PNAS..101.2584M. 

External links

• OR4E2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.