Biology:Pentalenene synthase
From HandWiki
| pentalenene synthase | |||||||||
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| Identifiers | |||||||||
| EC number | 4.2.3.7 | ||||||||
| CAS number | 90597-46-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme pentalenene synthase (EC 4.2.3.7) catalyzes the chemical reaction
- (2E,6E)-farnesyl diphosphate [math]\displaystyle{ \rightleftharpoons }[/math] pentalenene + diphosphate
This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, pentalenene-forming). This enzyme is also called pentalenene synthetase.
References
- Cane DE (1983). "Cell-free studies of monoterpene and sesquiterpene biosynthesis". Biochem. Soc. Trans. 11 (5): 510–5. PMID 6642060.
- "Pentalenene biosynthesis and the enzymic cyclization of farnesyl pyrophosphate". J. Am. Chem. Soc. 105: 122–124. 1983. doi:10.1021/ja00339a026.
- Cane, DE, Hubbard BR; Sohng, JK; Lamberson, CR; Rudnicki, SM; Wu, Z; Lloyd, MD; Oliver, JS; Hubbard, BR (1994). "Pentalenene synthase. Purification, molecular cloning, sequencing, and high-level expression in Escherichia coli of a terpenoid cyclase from Streptomyces UC5319". Biochemistry 33 (19): 5846–57. doi:10.1021/bi00185a024. PMID 8180213.
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