Biology:Phosphoethanolamine N-methyltransferase

From HandWiki
phosphoethanolamine N-methyltransferase
Identifiers
EC number2.1.1.103
CAS number171040-79-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a phosphoethanolamine N-methyltransferase (EC 2.1.1.103) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + ethanolamine phosphate [math]\displaystyle{ \rightleftharpoons }[/math] S-adenosyl-L-homocysteine + N-methylethanolamine phosphate

Thus, the two substrates of this enzyme are S-adenosyl methionine and ethanolamine phosphate, whereas its two products are S-adenosylhomocysteine and N-methylethanolamine phosphate.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase. This enzyme is also called phosphoethanolamine methyltransferase. This enzyme participates in glycerophospholipid metabolism.

References