Biology:RABEP1

From HandWiki
Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Rab GTPase-binding effector protein 1 is an enzyme that in humans is encoded by the RABEP1 gene.[1][2] It belongs to rabaptin protein family.

Interactions

RABEP1 has been shown to interact with:


References

  1. 1.0 1.1 "Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion". Cell 83 (3): 423–32. Nov 1995. doi:10.1016/0092-8674(95)90120-5. PMID 8521472. 
  2. "Entrez Gene: RABEP1 rabaptin, RAB GTPase binding effector protein 1". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9135. 
  3. 3.0 3.1 3.2 "Divalent interaction of the GGAs with the Rabaptin-5-Rabex-5 complex". The EMBO Journal 22 (1): 78–88. Jan 2003. doi:10.1093/emboj/cdg015. PMID 12505986. 
  4. "Structural basis for the accessory protein recruitment by the gamma-adaptin ear domain". Nature Structural Biology 9 (7): 527–31. Jul 2002. doi:10.1038/nsb808. PMID 12042876. 
  5. 5.0 5.1 "Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5". The EMBO Journal 17 (7): 1941–51. Apr 1998. doi:10.1093/emboj/17.7.1941. PMID 9524117. 
  6. "The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis". The Journal of Biological Chemistry 272 (10): 6097–100. Mar 1997. doi:10.1074/jbc.272.10.6097. PMID 9045618. 
  7. "Identification of rabaptin-5, rabex-5, and GM130 as putative effectors of rab33b, a regulator of retrograde traffic between the Golgi apparatus and ER". FEBS Letters 508 (2): 201–9. Nov 2001. doi:10.1016/s0014-5793(01)02993-3. PMID 11718716. 

Further reading