Biology:RacCS203

From HandWiki
RacCS203
Virus classification e
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Pisuviricota
Class: Pisoniviricetes
Order: Nidovirales
Family: Coronaviridae
Genus: Betacoronavirus
Subgenus: Sarbecovirus
Species:
Severe acute respiratory syndrome–related coronavirus
Strain:
RacCS203

RacCS203 is a bat-derived strain of severe acute respiratory syndrome–related coronavirus collected in acuminate horseshoe bats from sites in Thailand and sequenced by Lin-Fa Wang's team. It has 91.5% sequence similarity to SARS-CoV-2 and is most related to the RmYN02 strain. Its spike protein is closely related to RmYN02's spike, both highly divergent from SARS-CoV-2's spike.[1][2]

Phylogenetics

Phylogenetic tree

Genome comparison

SARS-CoV-2 compared to other SARSr-CoV (by nucleotide %)[3]
Strain Full-length genome ORF1ab S RBM ORF3a E M ORF6 ORF7a ORF7b ORF8 N ORF10
RaTG13 96.10% 96.50% 92.30% 86.30% 96.30% 99.60% 95.50% 98.40% 95.60% 99.20% 97.00% 96.90% 99.20%
RmYN02 93.60% 97.10% 72.50% 61.90% 96.40% 98.70% 94.80% 96.80% 96.20% 91.00% 48.70% 97.30% 99.20%
RacCS203 91.50% 94.30% 71.30% 61.60% 91.90% 99.10% 94.60% 96.20% 92.40% 93.90% 91.60% 93.20% 99.20%
GD/1/2019 90.20% 90.20% 83.70% 86.90% 93.20% 99.10% 93.30% 95.70% 93.40% 91.70% 92.10% 96.20% 99.20%
SL-ZC45 87.70% 89.00% 75.50% 62.50% 87.80% 98.70% 93.40% 94.60% 88.80% 94.70% 88.50% 91.10% 99.20%
SL-ZXC21 87.50% 88.70% 74.90% 61.60% 88.90% 98.70% 93.40% 94.60% 89.10% 95.50% 88.50% 91.20% 99.20%
GX-P4L 85.40% 84.80% 83.60% 80.00% 86.80% 97.40% 91.30% 90.90% 86.60% 83.50% 81.30% 91.00% 88.90%
GX-P5L 85.20% 84.60% 83.30% 79.90% 87.00% 97.40% 91.30% 90.90% 86.40% 83.50% 80.70% 91.00% 94.00%
SARS-CoV 79.30% 79.70% 72.30% 71.90% 75.30% 93.50% 85.50% 75.50% 82.10% 83.80% 45.80% 88.20% 93.20%
Rc-o319 79.20% 79.80% 72.20% 70.10% 83.30% 97.40% 86.60% 86.60% 78.40% 77.30% 52.30% 88.30% 94.90%
SARS-CoV-2 compared to other SARSr-CoV (by amino acid %)[3]
Strain Full-length genome ORF1ab S RBM ORF3a E M ORF6 ORF7a ORF7b ORF8 N ORF10
RaTG13 98.50% 97.30% 90.10% 97.80% 100.00% 99.60% 100.00% 97.50% 97.70% 95.00% 99.10% 97.40%
RmYN02 98.80% 72.40% 63.20% 96.70% 100.00% 98.70% 96.70% 95.90% 83.70% 28.20% 98.60% 97.40%
RacCS203 97.30% 72.30% 63.70% 97.50% 100.00% 99.10% 98.40% 95.90% 93.00% 94.20% 95.70% -
GD/1/2019 96.70% 90.00% 96.90% 97.10% 100.00% 98.70% 96.70% 97.50% 95.40% 95.00% 97.90% 97.40%
SL-ZC45 95.60% 80.20% 65.90% 90.90% 100.00% 98.70% 93.40% 87.60% 93.00% 94.20% 94.30% 97.40%
SL-ZXC21 95.20% 79.70% 65.90% 92.00% 100.00% 98.70% 93.40% 88.40% 93.00% 94.20% 94.30% -
GX-P4L 92.50% 92.30% 86.60% 89.50% 100.00% 98.20% 95.10% 88.40% - 87.60% 93.60% 73.70%
GX-P5L 92.50% 92.40% 86.60% 89.80% 100.00% 98.20% 95.10% 88.40% 72.10% 87.60% 93.80% 84.20%
SARS-CoV 86.10% 75.80% 73.10% 72.40% 94.70% 90.50% 67.20% 85.30% 81.40% - 90.50% 81.60%
Rc-o319 87.60% 76.20% 73.50% 87.00% 98.70% 91.00% 83.60% 73.80% 69.80% 26.80% 89.50% 86.80%

See also

  • RaTG13, 96.2% similarity to SARS-COV-2
  • RmYN02, 93.3% similarity to SARS-COV-2

References

  1. ↑ Wacharapluesadee, S; Tan, CW; Maneeorn, P; Duengkae, P; Zhu, F; Joyjinda, Y; Kaewpom, T; Chia, WN et al. (9 February 2021). "Evidence for SARS-CoV-2 related coronaviruses circulating in bats and pangolins in Southeast Asia.". Nature Communications 12 (1): 972. doi:10.1038/s41467-021-21240-1. PMID 33563978. Bibcode: 2021NatCo..12..972W. 
  2. ↑ "Coronavirus: Bat scientists find new evidence". 10 February 2021. https://www.bbc.com/news/science-environment-55998157. 
  3. ↑ Jump up to: 3.0 3.1 Wacharapluesadee, Supaporn; Tan, Chee Wah; Maneeorn, Patarapol; Duengkae, Prateep; Zhu, Feng; Joyjinda, Yutthana; Kaewpom, Thongchai; Chia, Wan Ni et al. (2021-02-09). "Evidence for SARS-CoV-2 related coronaviruses circulating in bats and pangolins in Southeast Asia" (in en). Nature Communications 12 (1): 972. doi:10.1038/s41467-021-21240-1. ISSN 2041-1723. PMID 33563978. Bibcode: 2021NatCo..12..972W. 

Wikidata ☰ Q105686530 entry



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