Biology:Rubber cis-polyprenylcistransferase
| rubber cis-polyprenylcistransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.5.1.20 | ||||||||
| CAS number | 62213-41-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a rubber cis-polyprenylcistransferase (EC 2.5.1.20) is an enzyme that catalyzes the chemical reaction
- poly-cis-polyprenyl diphosphate + isopentenyl diphosphate [math]\displaystyle{ \rightleftharpoons }[/math] diphosphate + a poly-cis-polyprenyl diphosphate longer by one C5 unit
Thus, the two substrates of this enzyme are poly-cis-polyprenyl diphosphate and isopentenyl diphosphate, whereas its two products are diphosphate and poly-cis-polyprenyl diphosphate longer by one C5 unit.
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is poly-cis-polyprenyl-diphosphate:isopentenyl-diphosphate polyprenylcistransferase. Other names in common use include rubber allyltransferase, rubber transferase, isopentenyl pyrophosphate cis-1,4-polyisoprenyl transferase, cis-prenyl transferase, rubber polymerase, and rubber prenyltransferase. This enzyme participates in biosynthesis of steroids.
References
- "Rubber transferase from Hevea brasiliensis latex". Methods Enzymol.. Methods in Enzymology 15: 476–480. 1969. doi:10.1016/S0076-6879(69)15018-1. ISBN 978-0-12-181872-2.
- "The biosynthesis of rubber: Incorporation of isopentenyl pyrophosphate into purified rubber particles by a soluble latex serum enzyme". The Biochemical Journal 101 (1): 42–7. October 1966. PMID 16742418.
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