Biology:Streptococcus gordonii
| Streptococcus gordonii | |
|---|---|
Scientific classification 
| |
| Domain: | Bacteria |
| Phylum: | Bacillota |
| Class: | Bacilli |
| Order: | Lactobacillales |
| Family: | Streptococcaceae |
| Genus: | Streptococcus |
| Species: | S. gordonii
|
| Binomial name | |
| Streptococcus gordonii Kilian et al. 1989
| |
Streptococcus gordonii is a Gram-positive bacterium included among some of the initial colonizers of the periodontal environment.[1] The organism, along with related oral streptococci, has a high affinity for molecules in the salivary pellicle (or coating) on tooth surfaces. S. gordonii therefore can rapidly colonize clean tooth surfaces, and S. gordonii along with related organisms comprise a high percentage, up to 70%, of the bacterial biofilm that forms on clean tooth surfaces. Generally harmless in the mouth, S. gordonii can cause acute bacterial endocarditis upon gaining access systemically. S. gordonii also forms an attachment substratum for later colonizers of tooth surface and can modulate the pathogenicity of these secondary colonizers through interspecies communication mechanisms.[citation needed]
The whole genome sequence of S. gordonii CCUG 33482 type strain was deposited and published in DNA Data Bank of Japan, European Nucleotide Archive and GenBank in 2016 under the accession number LQWV00000000.[2]
DNA repair
Upon systemic infection, S. gordonii is subjected to conditions in human blood that damage its DNA. However, DNA damage can be tolerated by the use of DNA repair processes.[3] The S. gordonii genome encodes a two protein complex, RexAB, that is employed in recombinational repair and can promote survival by repairing DNA double-strand breaks.[3]
References
- ↑ American Academy of Periodontology 2010 In-Service Exam, question 82
- ↑ Salvà-Serra, Francisco; Jakobsson, Hedvig E.; Thorell, Kaisa; Gonzales-Siles, Lucia; Hallbäck, Erika T.; Jaén-Luchoro, Daniel; Boulund, Fredrik; Sikora, Per et al. (2016-04-28). "Draft Genome Sequence of Streptococcus gordonii Type Strain CCUG 33482T" (in en). Genome Announcements 4 (2): e00175–16. doi:10.1128/genomeA.00175-16. ISSN 2169-8287. PMID 27013051.
- ↑ 3.0 3.1 Ha KP, Clarke RS, Kim GL, Brittan JL, Rowley JE, Mavridou DAI, Parker D, Clarke TB, Nobbs AH, Edwards AM. Staphylococcal DNA Repair Is Required for Infection. mBio. 2020 Nov 17;11(6):e02288-20. doi: 10.1128/mBio.02288-20. PMID 33203752; PMCID: PMC7683395
External links
Wikidata ☰ Q7623352 entry
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