Biology:Tocopherol O-methyltransferase

From HandWiki
tocopherol O-methyltransferase
Identifiers
EC number2.1.1.95
CAS number84788-82-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a tocopherol O-methyltransferase (EC 2.1.1.95) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + gamma-tocopherol [math]\displaystyle{ \rightleftharpoons }[/math] S-adenosyl-L-homocysteine + alpha-tocopherol

Thus, the two substrates of this enzyme are S-adenosyl methionine and gamma-tocopherol, whereas its two products are S-adenosylhomocysteine and alpha-tocopherol.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:gamma-tocopherol 5-O-methyltransferase. This enzyme is also called gamma-tocopherol methyltransferase. This enzyme participates in biosynthesis of steroids.

References

  • "Demonstration and solubilization of S-adenosylmethionine - gamma-tocopherol methyltransferase from capsicum chromoplasts". Plant Cell Rep. 4: 31–32. 1985. doi:10.1007/BF00285499.