Biology:Tryptophan dimethylallyltransferase
tryptophan dimethylallyltransferase | |||||||||
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Identifiers | |||||||||
EC number | 2.5.1.34 | ||||||||
CAS number | 55127-01-0 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a tryptophan dimethylallyltransferase (EC 2.5.1.34) is an enzyme that catalyzes the chemical reaction
- dimethylallyl diphosphate + L-tryptophan [math]\displaystyle{ \rightleftharpoons }[/math] diphosphate + 4-(3-methylbut-2-enyl)-L-tryptophan
Thus, the two substrates of this enzyme are dimethylallyl diphosphate and L-tryptophan, whereas its two products are diphosphate and 4-(3-methylbut-2-enyl)-L-tryptophan.
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is dimethylallyl-diphosphate:L-tryptophan dimethylallyltransferase. Other names in common use include dimethylallylpyrophosphate:L-tryptophan dimethylallyltransferase, dimethylallyltryptophan synthetase, dimethylallylpyrophosphate:tryptophan dimethylallyl transferase, DMAT synthetase, and 4-(gamma,gamma-dimethylallyl)tryptophan synthase.
References
- "Purification and properties of dimethylallylpyrophosphate:tryptopharm dimethylallyl transferase, the first enzyme of ergot alkaloid biosynthesis in Claviceps. sp. SD 58". Arch. Biochem. Biophys. 177 (1): 84–94. 1976. doi:10.1016/0003-9861(76)90418-5. PMID 999297.
Original source: https://en.wikipedia.org/wiki/Tryptophan dimethylallyltransferase.
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