Biology:Uracilylalanine synthase
| Uracilylalanine synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.5.1.53 | ||||||||
| CAS number | 113573-73-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Uracilylalanine synthase (EC 2.5.1.53) is an enzyme that catalyzes the chemical reaction
- REDIRECT Template:Chemical reaction
The two substrates of this plant enzyme are O-acetylserine and uracil. Its products are acetic acid and willardine.[1] The enzyme has been characterised from pea.[2] Although it transfers a 2-amino-2-carboxyethyl group from O-acetylserine, it has been shown not to be the same protein as cysteine synthase.[3]
This enzyme is a transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is O3-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase. Other names in common use include O3-acetyl-L-serine acetate-lyase (adding uracil), isowillardiine synthase, willardiine synthase, and 3-O-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase.[4]
References
- ↑ Kuo, YH; Lambein F (1978). "Biosynthesis of the uracilylalanines willardiine and isowillardiine in higher plants". Phytochemistry 17 (9): 1571–1576. doi:10.1016/S0031-9422(00)94645-4. Bibcode: 1978PChem..17.1571M.
- ↑ Ahmmad MAS; Maskall CS; Brown EG (1984). "Partial-purification and properties of willardiine and synthase activity from Pisum sativum". Phytochemistry 23 (2): 265–270. doi:10.1016/S0031-9422(00)80315-5.
- ↑ "Difference between uracilylalanine synthases and cysteine synthases in Pisum sativum". Phytochemistry 26 (10): 2699–2704. 1987. doi:10.1016/S0031-9422(00)83575-X. Bibcode: 1987PChem..26.2699I.
- ↑ Enzyme 2.5.1.53 at KEGG Pathway Database.
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