Biology:Uracilylalanine synthase
From HandWiki
Short description: Class of enzymes
| uracilylalanine synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.5.1.53 | ||||||||
| CAS number | 113573-73-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, an uracilylalanine synthase (EC 2.5.1.53) is an enzyme that catalyzes the chemical reaction
- O3-acetyl-L-serine + uracil [math]\displaystyle{ \rightleftharpoons }[/math] 3-(uracil-1-yl)-L-alanine + acetate
Thus, the two substrates of this enzyme are O3-acetyl-L-serine and uracil, whereas its two products are 3-(uracil-1-yl)-L-alanine and acetate.
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is O3-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase. Other names in common use include O3-acetyl-L-serine acetate-lyase (adding uracil), isowillardiine synthase, willardiine synthase, and 3-O-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase.
References
- Ahmmad MAS; Maskall CS; Brown EG (1984). "Partial-purification and properties of willardiine and synthase activity from Pisum sativum". Phytochemistry 23 (2): 265–270. doi:10.1016/S0031-9422(00)80315-5.
- "Difference between uracilylalanine synthases and cysteine synthases in Pisum sativum". Phytochemistry 26 (10): 2699–2704. 1987. doi:10.1016/S0031-9422(00)83575-X.
- Kuo, YH; Lambein F (1978). "Biosynthesis of the uracilylalanines willardiine and isowillardiine in higher plants". Phytochemistry 17 (9): 1571–1576. doi:10.1016/S0031-9422(00)94645-4.
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