Chemistry:1-Chlorobutane
From HandWiki
1-Chlorobutane is an alkyl halide with the chemical formula C4H9Cl. It is a colorless, flammable liquid. It is used as a solvent in some industries due to its ability to dissolve both polar and non-polar substances.[1] It is an alkylating reagent, that is used in organic synthesis to add a butyl group to other molecules.[2]
Preparation and reactions
It can be prepared from 1-butanol by treatment with hydrogen chloride:[3]
- C4H9OH + HCl → C4H9Cl + H2O
It reacts with lithium metal to give n-butyllithium:[4]
- 2 Li + C4H9Cl → C4H9Li + LiCl
1-Chlorobutane reacts with sodium hydroxide via nucleophilic substitution to produce butanol:
- C4H9Cl + NaOH → C4H9OH + NaCl
References
- ↑ "What is 1-Chlorobutane? Uses, Properties, and Safety? - Pioneer" (in en). https://www.pioneerbioinc.com/.
- ↑ "The Role of 1-Chlorobutane in Modern Organic Synthesis: A Deep Dive". https://www.nbinno.com/article/other-organic-chemicals/the-role-of-1-chlorobutane-in-modern-organic-synthesis-a-deep-dive-mn.
- ↑ Copenhaver, J. E.; Whaley, A. M. (1925). "N-Butyl Chloride". Organic Syntheses 5: 27. doi:10.15227/orgsyn.005.0027.
- ↑ Brandsma, L.; Verkraijsse, H. D. (1987). Preparative Polar Organometallic Chemistry I. Berlin: Springer-Verlag. ISBN 3-540-16916-4.
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