Chemistry:1-Indanone

1-Indanone

Names
Preferred IUPAC name 2,3-Dihydro-1H-inden-1-one
Other names α-Hydroindone
Identifiers
CAS Number	83-33-0
3D model (JSmol)	Interactive image
3DMet	B00309
Beilstein Reference	507957
ChEBI	CHEBI:17404
ChemSpider	6479
EC Number	201-470-1
Gmelin Reference	142414
KEGG	C01504
PubChem CID	6735
UNII	V7021Y717I
InChI InChI=1S/C9H8O/c10-9-6-5-7-3-1-2-4-8(7)9/h1-4H,5-6H2 Key: QNXSIUBBGPHDDE-UHFFFAOYSA-N
SMILES C1CC(=O)C2=CC=CC=C21
Properties
Chemical formula	C9H8O
Molar mass	132.162 g·mol−1
Appearance	Colorless solid
Melting point	38–42 °C (100–108 °F; 311–315 K)
Boiling point	243–245 °C (469–473 °F; 516–518 K)
Hazards
GHS pictograms
GHS Signal word	Warning
GHS hazard statements	H302
GHS precautionary statements	P261, P264, P270, P271, P280, P301+312, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362, P403+233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Tracking categories (test):

• SizeSet

1-Indanone is the organic compound with the formula C₆H₄(CH₂)₂CO. It is one of two isomeric benzocyclopentanones, the other being 2-indanone. It is a colorless solid. 1-Indanone is a substrate for the enzyme indanol dehydrogenase.

Preparation

It is prepared by oxidation of indane or indene. It can also be prepared by cyclization of phenylpropionic acid.

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List of Drugs

1. 2-Aminoindan synthesis (MDAI methodology using beta-keto-oxime formation with isoamylnitrite followed by reduction)
2. Drinidene
3. LNK-121
4. Pirandamine
5. Pyrophendane
6. SKF Derivatives
7. Indane analog of nisoxetine or Prozac.